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蒋成

作者: 时间:2023-09-11 点击数:

蒋成,男,汉族。2009年6月本科毕业于河西学院生物工程专业,获工学学士学位;2012年7月硕士研究生毕业于华南师范大学生物物理学专业,获理学硕士学位;2016年9月于澳大利亚新南威尔士大学化学专业获理学博士学位,2017-2022年在英国牛津大学临床神经科学系(John Redcliffe医院)从事博士后研究。现为香港中文大学(深圳)医学院助理教授(副研究员),校长青年学者,博士生&博士后合作导师;深圳市和广东省高层次人才。主要研究方向为疑难疾病的生物标志物开发,特别是针对尚无有效标志物的神经退行性疾病(比如帕金森病)的精准诊断。2017-2022曾先后主持或共同主持包括John Fell Fund、The Michael J. Fox Foundation Grant。凭借在高、低通量检测技术及帕金森病标志物开发方面的工作,蒋成博士在2020和2022年分别荣获牛津大学临床神经科学系Thomas Wills Early Career Researcher Prize和Recognition of Research Excellence Award,2024年带领团队获得广东省生物医学工程创新创业大赛二等奖。现以一作/通讯作者在Chem Rev(高被引文章, 2020最受读者喜爱的五佳论文), Mov. Disord(入选插图文章); J. Neurol. Neurosurg. Psychiatry(高被引文章);VIEW(入选主封面论文), Biomedical Analysis (入选主封面论文), Micro-Nano Lett (高被引文章), Adv. Mater, Adv. Funct Mater, ACS AMI, Anal Chem,ACS Sens,Nanoscale Horiz, Mater. Chem. Front, Biosens. Bioelectron, ACS Appl. Nano Mater, Dyes Pigm, Langmuir, EVCNA等国际著名期刊上发表论文70余篇以及应邀撰写两个BOOK Chapter。已获得国内外专利授权5项。同时担任40过个SCI 杂志特邀审稿人以及细胞外囊泡与循环核酸 (Extracellular Vesicles and Circulating Nucleic Acids, EVCNA)、Brain-X、Asian J Pharm Sci青年编委和Biosensors and Bioelectronics, Photonics, Micromachines等杂志客座编辑。回国后获得国自然面上和广东省基础研究基金等多个项目资助。

联系方式为:Email: jiangcheng@cuhk.edu.cn

一、 近期以第一作者或通讯作者发表的主要论文

1. Xiang,Z., Wei, C., Zhu, S., Liu, S., Zhang, R., Tong, X., Wang, Z., Deng, J., Zhang, X., Lingfeng Zhong, L., Sun, R., Hou, Y., Jiang, C.,* Zhang, Y.,*, Luo, Y.,* Zang, G.,* (2025). From Detection to Mechanistic Insight: Electrochemiluminescence as a Universal Platform for Reaction Kinetics. Biosensors and Bioelectronics (IF 10.61, 共同通讯)

2. Lu, Y., Liu, Y., LIU, C., Zhou, Y., Wan, Y., Wang, Y., Li, L., Luo, X., Jing, S., Li, M., Li, S., Xu, R., Zheng, Y., Li, C. Z., Zhao, Z.,* Jing, C.,* Tang, B. Z.* (2025) Advanced Functional Materials. (e19715, IF 19.0, 共同通讯)

3. Zhang, Wenjing, Ting Zhang, Jiayu Ding, Jingwen Cao, Zheyan He, Yanling Liu, Yong Juan Zhao, Jiang, C.* (2025) The PRIDE system: A photo-responsive platform for high-efficiency isolation of extracellular vesicles for Parkinson's disease diagnostics. Chemical Engineering Journal: 167006. (IF 13.2, 末位通讯)

4. Lin, L., Xue, Y., Tan, L., Jiang, C., Liu, M., Li, X., ... & Shu, B. (2025). Micro-scale thermofluidics enable autonomous and scalable CRISPR diagnostics for sexually transmitted infections screening. Biosensors and Bioelectronics, 117591. (IF 10.61, 共同一作)

5. Lu, Y., Liu, C., Liu, Y., Gu, H., Luo, X., Jiang, C*., ... & Tang, B. Z. (2025). Detection of carcinoembryonic antigen using aggregation-induced emission luminogens empowered triple-format biosensor. Biosensors and Bioelectronics, 272, 117065. (IF 10.61, 共同通讯)

6. Zheng, J., Jiang, X., Bai, S., Lai, M., Yu, J., Chen, M., Jiang, C*.. & Guo, K*. (2025). Clinically Accurate Diagnosis of Alzheimer's Disease via Single‐Molecule Bioelectronic Label‐Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers. Advanced Materials, 2505262. (IF 26.8, 共同通讯)

7. Zhou, Y., Lai, M., Shu, B., Wang, B., Wang, D., Liu, H., ... & Jiang, C.* (2025). Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson's disease. Theranostics, 15(15), 7409. (IF 13.3, 末位通讯)

8. Yan, S., Zhang, W., Li, X., Dutta, S., Castle, A. R., Liu, Yi., Sahoo, A., Chor Lai Lam1,5, Gatford, N.J. F., Hu, M.T., Li, C-Z., Jiang, C.* Shu, B.,* Tofaris, G.K.* (2025) Single extracellular vesicle detection assay identifies membrane-associated α-Synuclein as an early-stage biomarker in Parkinson’s disease. Cell Reports Medicine DOI 10.1016/j.xcrm.2025.101999 (IF 11.7共同通讯)

9. Wu, C., Yi, J., Liu, H., Xie, J., Liu, H., Chen, Z., Wang, X., Zhou, Y., Li, C.* and Jiang, C.*, (2025). A dual-mode paper-based microfluidic chip for protamine detection. Biomedical Analysis. doi.org/10.1016/j.bioana.2025.10.001 . (末位通讯, 被选为正封面论文)

10. Chen, W., Guan, H., Lu, Y., Zeng, G., Gu, Di., Guo, K.,* Jiang, C.,* Liu, H* (2025). Harnessing aggregation-induced emission based detection toolbox for diagnostics of urogenital tumors. Aggregate. DOI doi: 10.1002/agt2.70008, (IF13.7共同通讯)

11. Zhou, Y., Yan, S., Dong, W., Wu, C., Zhao, Z., Wang, R., Duo, Y., Huang, Y., Xu, D. and Jiang, C.,* (2023). Biosensing strategies for amyloid‐like protein aggregates. BMEMat, p.e12053. (IF15.5, 末位通讯)

12. Yan, S., Jiang, C., Janzen, A., Barber, T.R., Seger, A., Sommerauer, M., Davis, J.J., Marek, K., Hu, M.T., Oertel, W.H. and Tofaris, G.K., (2023). Neuronally derived extracellular vesicle α-synuclein as a serum biomarker for individuals at risk of developing Parkinson disease. JAMA Neurology. (ESI高被引,IF 21.3, 并列一作,highlighted by BBC and Nat Rev Neurology)

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